Finished Product

VAR-1002

Vet Systems - Small Animal

Product

Defects in articular cartilage can induce osteoarthritis by causing molecular changes in the synovial fluid. Research in molecular biology discovered the major inducer of osteoarthritis was the general inflammatory cytokine interleukin-1 (IL-1) which plays a key role in accelerating tissue destruction and the repair mechanisms.
 
In a healthy joint, IL-1 and interleukin-1 receptor antagonist (IL-1Ra) are in balanced concentrations. In cases of osteoarthritis, there is not sufficient IL-1Ra produced to block the destructive effects of the increased IL-1. The result is inflammation, joint pain, and eventually cartilage destruction. In the IRAP II system, monocytes (a type of white blood cell) bind to the glass beads. The cells are then stimulated to produce regenerative and anti-inflammatory proteins without the addition of drugs. This process takes place over an incubation period of 24 hours.
 
IRAP II is used to treat mild to moderate osteoarthritis in animals.

IRAP II™ System

Child (D)

Vet Systems - Orthobiologics

Defects in articular cartilage can induce osteoarthritis by causing molecular changes in the synovial fluid. Research in molecular biology discovered the major inducer of osteoarthritis was the general inflammatory cytokine interleukin-1 (IL-1), which plays a key role in accelerating tissue destruction and the repair mechanisms.
 
In a healthy joint, IL-1 and interleukin-1 receptor antagonist (IL-1Ra) are in balanced concentrations. In osteoarthritis, the IL-1Ra produced is insufficient to block the destructive effects of the increased IL-1. The result is inflammation, joint pain, and eventually cartilage destruction. Using the Arthrex IRAP™ ProEAS system, monocytes (a type of white blood cell) from the animal’s harvested blood bind to the glass beads in the device. The cells are stimulated over 24 hours of incubation to produce regenerative and anti-inflammatory proteins without the addition of drugs. The autologous serum produced using the Arthrex IRAP ProEAS device may be used to treat mild to moderate osteoarthritis in animals.

Veterinary Incubator of Arthrex IRAP ProEAS System

VAR-1002

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Small Animal

IRAP II™ System

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Orthobiologics

IRAP ProEAS™ System

Product